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Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases

Dr. Pankaj Malukani, Dr. R. N. Gonsai, Dr. Richa Sharma, Dr. Hemina Desai, Dr. H. M. Goswami, Dr. Nirav Hingrajia.

Abstract
Introduction: Dysfunctional uterine bleeding (DUB) is a common problem in women in the 30-50 years age group. The incidence increases as age advances till menopause. The pathophysiology is not fully understood and it is complex. It accounts for above one third of all gynaecological consultations carried out for abnormal uterine bleeding. Objectives: To study correlation of different clinical presentation and clinical findings with histopathology of endometrium in cases of Dysfunctional Uterine Bleeding (DUB). Results: A one year retrospective study of DUB cases was conducted in Department of Pathology, B.J. Medical College, Ahmedabad. 400 cases were studied which were clinically diagnosed as DUB with exclusion of structural lesions by radiological investigations and proven histologically. Dilatation and curettage (D & C) was the commonest mode by which endometrium was obtained (79% cases). Largest numbers of patients were in 31-40 years (48%) with mean age being 38.7 years. The most common clinical presentation was menorrhagia (76.5%) followed by Metrorrhagia (13.5%). In present series proliferative phase was most common and found in 39.75% cases. Hyperplasia was seen in 22% cases. Atypical hyperplasia was a rare finding (4.55%). Conclusion: The patient who presents with DUB and a history of menstrual cycle irregularity warrants an endometrial biopsy, regardless of age. A higher degree of suspicion, based on clinical findings and associated risk factors, precise histological typing of lesions and to rule out organic causes is essential in the management of DUB.

Key words: Dilatation & Curettage, Dysfunctional Uterine Bleeding, Endometrium, Hysterectomy


 
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How to Cite this Article
Pubmed Style

Malukani DP, Gonsai DRN, Sharma DR, Desai DH, Goswami DHM, Hingrajia DN. Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases . SEAJCRR. 2013; 2(6): 429-435.



Web Style

Malukani DP, Gonsai DRN, Sharma DR, Desai DH, Goswami DHM, Hingrajia DN. Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases . www.scopemed.org/?mno=149801 [Access: October 22, 2017].



AMA (American Medical Association) Style

Malukani DP, Gonsai DRN, Sharma DR, Desai DH, Goswami DHM, Hingrajia DN. Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases . SEAJCRR. 2013; 2(6): 429-435.



Vancouver/ICMJE Style

Malukani DP, Gonsai DRN, Sharma DR, Desai DH, Goswami DHM, Hingrajia DN. Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases . SEAJCRR. (2013), [cited October 22, 2017]; 2(6): 429-435.



Harvard Style

Malukani, D. P., Gonsai, D. R. N., Sharma, D. R., Desai, D. H., Goswami, D. H. M. & Hingrajia, D. N. (2013) Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases . SEAJCRR, 2 (6), 429-435.



Turabian Style

Malukani, Dr. Pankaj, Dr. R. N. Gonsai, Dr. Richa Sharma, Dr. Hemina Desai, Dr. H. M. Goswami, and Dr. Nirav Hingrajia. 2013. Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases . The Southeast Asian Journal of Case Report and Review, 2 (6), 429-435.



Chicago Style

Malukani, Dr. Pankaj, Dr. R. N. Gonsai, Dr. Richa Sharma, Dr. Hemina Desai, Dr. H. M. Goswami, and Dr. Nirav Hingrajia. "Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases ." The Southeast Asian Journal of Case Report and Review 2 (2013), 429-435.



MLA (The Modern Language Association) Style

Malukani, Dr. Pankaj, Dr. R. N. Gonsai, Dr. Richa Sharma, Dr. Hemina Desai, Dr. H. M. Goswami, and Dr. Nirav Hingrajia. "Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases ." The Southeast Asian Journal of Case Report and Review 2.6 (2013), 429-435. Print.



APA (American Psychological Association) Style

Malukani, D. P., Gonsai, D. R. N., Sharma, D. R., Desai, D. H., Goswami, D. H. M. & Hingrajia, D. N. (2013) Histo-Pathological Study of Endometrium in Dysfunctional Uterine Bleeding- A Study of 400 Cases . The Southeast Asian Journal of Case Report and Review, 2 (6), 429-435.



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